Studies eligible for co-enrolment with OPTIMISE II

Effective 2nd April 2019

• Add Aspirin Trial

• A phase III, double blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non metastatic solid tumours. ISRCTN: 74358648

• The CIPHER Study

• UK Cohort study to Investigate the prevention of Parastomal Hernia (Phase B). ISRCTN: 17573805

• PQIP

• National Perioperative Quality Improvement Programme to measure care delivered, complications and outcome from the patient perspective after major surgery.

• The ROCKet Trial

• Reduction of Chronic Post-surgical Pain with Ketamine - phase 3/4 randomised controlled trial of the effect of up to 72 hours of perioperative ketamine on the risk of development of chronic post-surgical pain.

• WesFit

• To investigate the efficacy of a community based Structured Responsive Exercise-training Programme (SRETP) ± psychological support on surgical outcome by reducing postoperative length of stay (LOS) and complications. ClinicalTrials.gov Identifier: NCT03509428

• CAPOEIRA

• Cohort study to investigate whether giving patients intravenous iron improves their fitness. ClinicalTrials.gov Identifier: NCT03346213

• GAP Study

• Gabapentin in postsurgical pain. ISRCTN: 63614165

• INTACT Study

• A feasibility, open-label, randomised controlled trial of intravenous iron versus usual care in survivors of intensive care with moderate and severe anaemia. ISRCTN: 13721808